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Protein acylation: mechanisms, biological functions and therapeutic targets

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Although different cancer types are affected to diverse extents by cachexia, about 80% of all cancer patients experience this comorbidity, which highly reduces quality of life and response to therapy, and worsens prognosis, accounting for more than 25% of all cancer deaths

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Importantly, this pediatric-focused study showed that miRNA alterations start early and are not restricted to adult populations, suggesting that miRNA panels could help with early detection and prevention strategies in adolescents