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Shi R, Dong S, Mao J, Wang J, Cao Z, Wang Y, et al

Adding to doctors worries are concerns about purity and dosing, because users typically buy from websites selling unregulated Chinese product some of which comes from plants that previously produced the deadly opioid fentanyl

Funding This study was supported by the State Key Laboratory of Trauma, Burn and Combined Injury (SKLYQ202002 to YC), Southwest Hospital (SWH2018BJKJ-05 to YC), National Natural Science Foundation of China (82030036 to HF), and Chongqing Talent Program (4139Z2391 to HF)

229 Conversely, SIRT1 facilitates transcriptional activation of the BECN1 gene by deacetylating histone H4 at lysine 16, thereby establishing a chromatin configuration permissive for autophagy induction under nutrient-deprived conditions