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Pharmaceutics 17:281

Drug delivery systems based on HA also face difficulties with controlling release kinetics, ensuring efficient cellular uptake, and overcoming tumor heterogeneity, as not all cancer cells overexpress CD44 receptors targeted by HA conjugates

Furthermore, the observed increment of ATPase activity seen after GB treatment suggests that ATPase activity functions to mitigate the effect of Cr ions on the plasma membrane of the plants

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Combined, they produce synergistic GH elevation that is more consistent than either peptide alone (Veldhuis et al., 2012)