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NNMT Expression in Metabolic Disease

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Commonly investigated in dermatology and biomaterials research, AHK-Cu is used in models focused on collagen/elastin dynamics, inflammatory signaling balance, and oxidative-stress response.

The study of pernicious anemia patients with relapse of anemia (Figure 10) (53) has shown that the depletion of serum vitamin B-12 after folic acid administration is accompanied by a proportional increase in reticulocyte counts, suggesting that serum vitamin B-12 is diverted into the hematopoietic system to provide the necessary vitamin B-12 coenzyme for methionine production

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