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Blinding was not performed during animal experiments and data collection, but outcome assessments (e.g., IHC scoring) were conducted by blinded investigators

Yet, measures of specific neuropathic impairments (secondary outcomes) improved with lipoic acid supplementation (78)

2021;372(6547):1224 to 1229

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In glaucoma, alterations in the ON head due to increased IOP also include reduced blood flow, oxidative stress, reactive gliosis, as well as remodeling of the extracellular matrix (Tamm et al., 2017)