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13422-55-4 Appearance Solid Molecular Weight 1344.38 Formula C 63 H 91 CoN 13 O 14 P Color Brown to red SMILES C[C@]1([C@](C)2CC(N)=O)[N]([Co+3]([N](C([C@](C)3CC(N)=O)=C4C)=C5[C@H]3CCC(N)=O)([N](C(C(C)6C)=C5)=C([C@H]6CCC(N)=O)C(C)=C7[C@@]8(CCC(NC[C@H]9C)=O)C)([N](C%10=C%11)=CN([C@@H](O[C@@H]%12CO)[C@]([C@@H]%12O[P]([O-])(O9)=O)([H])O)C%10=CC(C)=C%11C)[N-]7[C@]1([H])[C@@H]8CC(N)=O)=C4[C@H]2CCC(N)=O.[CH3-] Synonyms Mecobalamin

Particularly important for vegans and older individuals, low B12 serum levels can contribute to certain neurological diseases, like Alzheimers, dementia, and cardiovascular disease

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The method of claim 56, wherein all the amino acid codons in the antigen binding site are mutagenized and a set of degenerate oligonucleotides that encode all nineteen naturally-occurring amino acid variants are provided for each amino acid codon mutagenized

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