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Prognostic Factors Affecting Risk-Based Treatment Patient and clinical disease characteristics Patient and clinical disease characteristics affecting prognosis include the following: Age at diagnosis Age at diagnosis has strong prognostic significance in patients with B-ALL, reflecting the different underlying biology of ALL in different age groups.[7] Age at diagnosis is not prognostically relevant in T-ALL.[8] Infants (younger than 1 year)

5B-D), and the protein expressions of IBA-1 and IKBKB in the dorsal horn of the spinal cord, were decreased (Fig

doi: 10.1016/j.jnutbio.2010.07.009 66 WangPTaoWLiQMaWJiaWKangY

81473198 to JGC), Science Fund for Creative Research Groups of the Natural Science Foundation of Hubei Province (2015CFA020) and PCSIRT (No

Apart from age, sex and race, other consistent risk factors were identified such as chronic inflammation related meibomian gland dysfunction and Demodex eyelid infestation, connective tissue disease, conditions that may worsen tear stability and ocular surface (34, 35)