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Animal studies of colitis have shown KPV significantly reduces gut inflammation, body weight loss, and pro-inflammatory cytokine activity

As a result, the ETC functioning is disrupted, and ATP content becomes significantly depleted, which breaks down metabolic and ionic homeostasis and activates the degradative enzymes such as nucleases, proteases, and phospholipases [182, 188]

This metabolic shift is crucial for the growth and maintenance of cancer cells, especially in tumor stem cells (CSCs) or cells with stem-like properties, which often exhibit increased glycolytic activity

FOR FURTHER INFORMATION CONTACT: Regulation coordination questions, contact Gina Aughenbaugh via email at 410-786-7756 or [email protected]

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