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326 Specifically, IFN- impedes neutrophil accumulation by downregulating the expression of CXCR2 and CXCR4 on tumor cells, thereby disrupting the binding of their corresponding ligands

[3] Role of the Rapoport-Luebering shunt The Rapoport-Luebering shunt leads to the formation of 2,3-BPG, an allosteric effector of hemoglobin , along with carbon dioxide and hydrogen ions

Loryan I, Sinha V, Mackie C, Van Peer A, Drinkenburg W, Vermeulen A, Morrison D, Monshouwer M, Heald D, Hammarlund-Udenaes M

euphoria , sedation , muscle relaxation, hypotension , bradycardia , & decreased perception of pain It may also affect 1 adrenergic, histamine, serotonin, and opioid receptors (Hoffman et al, 2001

For the full show notes, including the episode transcript (available exclusively to Huberman Lab Premium members), please visit hubermanlab.com