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(1) Statins diminish respiratory capacity at the level of complexes I (CI), II (CII), and III (CIII) of the respiratory chain, which in turn results in the increased generation of superoxide (O 2 ) generation

Incremento del VO2 max

Effect of Race The effects of race on the kinetics of valproate have not been studied

Quality assessment Randomized controlled trials were assessed using GRADE methodology

Therewith, Pompili and colleagues [43], evidenced the correlation between PPAR activation and mitigation of senescence markers including -gal, laminin b1, and SASP members in colonic mucosa biopsies obtained from patients with inflammatory bowel disease, and in a mouse model of colitis induced by dextran-sodium-sulphate