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Common withdrawal symptoms can include anxiety, headaches, shaky hands, and insomnia

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Comment: One commenter noted that our proposal and the second alternative do not address situations in which price ( concessions significantly reduce the ASP-based payment limit but the payment limit is still positive, and urged that we pursue either a legislative proposal to exclude certain rebates from payment limit calculations, discussed further below in section III.A.2.h of this rule, or the first alternative considered

Methylene blue can enter the brain by crossing the protective tissue barrier that surrounds it