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The Cu2+ ion is coordinated by the histidine imidazole nitrogen and the N-terminal amino group of glycine, forming a specific metal-peptide complex

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Long-term users report sustained results with continued use, often noting that they've maintained improvements for years when copper peptides remained part of their routine

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Quick Answer Neither peptide is objectively "better." Available studies indicate Semax is a powerful cognitive enhancer that works primarily by upregulating Brain-Derived Neurotrophic Factor (BDNF) to improve memory, focus, and stroke recovery