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10.1111/jdi.12678 63 KietzmannT.PetryA.ShvetsovaA.GerholdJ

The immunosuppressive properties of ferroptosis coupled with inflammatory responses triggered by therapy-induced tissue damage potentially drive tumor progression (Dang 2022

10.33594/000000396 51 DinklaS.van EijkL

unlike antibody-mediated endocytosis, cellular uptake is highly variable, depending critically on the intrinsic trafficking of the target protein or on non-specific pinocytosis, representing a major bottleneck in achieving therapeutically relevant intracellular concentrations of the PROTAC payload (Table 2) [244]