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Description

Laryngoscope 111, 528534

321 Ligandreceptor binding results in the release of the Notch intracellular domain (NICD) and NICD interaction with recombination signal-binding protein immunoglobulin kappa J (RBPJ) to initiate the transcription of downstream target genes such as HES/HEY

Within the latter of marker molecules with known molecular weight such as Albumin and the analytical GAD 65 molecule purisimum and in spiking experiments, the existence of GAD 65 can be estimated