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While there is a theoretical risk that CP antibodies could enhance disease via ADE, case reports in SARS-CoV and MERS-CoV outbreaks showed that CP therapy was safe and was associated with improved clinical outcomes 89,90

it also reduced the risk of death or worsening disease by 33% versus chemotherapy

The pentose phosphate pathway, by generating NADPH, plays a crucial role in replenishing reduced glutathione levels, safeguarding the cell from oxidative damage and ensuring cellular survival and function

This result is suggestive of the constitutive activation of LKB1/AMPK pathway in the livers of KO mice

Its especially important to adhere to safety guidelines for eye drops after a 2023 recall of certain over-the-counter brands of artificial tears lubricant eye drops and artificial eye ointment