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IM injections allow nutrients to enter the bloodstream more efficiently than oral supplements, which must pass through the digestive system and may have lower absorption rates

But even a real, known risk may draw no regulatory action because its another regulators job or because acting is resource-intensive, costly and may not achieve the aim of making patients safer

For example, intra-articular injection of CpG-ODNs in animal models has been shown to induce arthritis in vivo

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