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SKU: 8596905769
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Description

Int J Pharm 515:132164

N., de Santana J

Dual inhibition of GGCT and xCT induces ferroptosis through cysteine depletion and redox collapse To investigate the mechanism by which the combination of pro-GA and erastin induces ferroptosis, we assessed whether the mechanism involved disrupting intracellular redox homeostasis

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First-in-human phase I study of the oral inhibitor of indoleamine 2,3-dioxygenase-1 epacadostat (INCB024360) in patients with advanced solid malignancies