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10.1002/mds.24962 Mov

Therefore, astrocytes have emerged as a key component of the CNS vascular system, where they regulate the transfer of metabolites from the blood, communicate with the peripheral immune system, maintain the integrity of BBB, regulate homeostasis, and initiate blood vessel contractility phenomenon upon a neuronal activity (Cohen-Salmon et al., 2021)

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Although PPAR, a key transcriptional regulator of adipogenesis and lipid metabolism, showed only a modest increase in EiaKO BAT, the elevated levels of its downstream target FABP4 suggested a compensatory response to lipid overload resulting from impaired mitochondrial fatty acid utilization (Fig

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