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This updated burden estimate is a decrease of 960 hours [(3,200 HOPDs 0.167 hours 2 quarters)(3,200 HOPDs 20 percent 0.167 hours 1 quarter)] at a savings of $52,858 (960 hours $55.06) for the CY 2027 reporting period, and a decrease of 2,027 hours [(3,200 HOPDs 20 percent 0.167 hours 3 quarters) + (3,200 HOPDs 80 percent 0.167 hours 4 quarters)] at a savings of $111,607 (2,027 hours $55.06/hour) annually beginning with the CY 2028 reporting period

Neurobiol Aging 33:824.e516

The main driver of the gap is the data collection periods for the individual measures which is outside the purview of the Overall Hospital Quality Star Rating methodology, and often necessary as longer periods are needed for smaller volume hospitals

[7] The effects of high-dose NAD+ on a developing fetus or nursing infant have not been studied, so the therapy is avoided entirely in these situations out of caution

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