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The expression of arginases including ARG1 and ARG2 has been reported to be increased in cancers, such as gastric cancer, breast cancer, prostate cancer, colorectal cancer, and AML (Leu and Wang, 1992

10.1093/bioinformatics/btp101 34

4.3 NO-releasing agents in overcoming tumor hypoxia Tumor hypoxia, a hallmark of solid malignancies such as CRC, drives therapeutic resistance, immunosuppression, and metastasis

*Correspondence: Dipak Kumar Sahoo, [email protected]

TB-500 also suppresses apoptosis, reduces pro-inflammatory cytokine activity, and has been shown to upregulate VEGF and actin-binding proteins to initiate new capillary formation making it a complementary partner to BPC-157s vascular network organisation activity in combined tissue repair pathway research