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The effects of smoking are well-established and contradictorysignificantly increasing the risk of CD, disease activity, and the need for surgery/hospitalization [173, 278], However, smoking demonstrates a protective effect in UC [173, 279], and the risk of relapse in UC increases immediately after smoking cessation [280, 281], It may also amplify the effects of certain genetic variations through gene-environment interactions [282]

Speaking of anorexia, another study found that the combined use of carnitine and adenosyl B12 eliminated fluctuations in work rate, and normalized the scope and productivity of intellectual work in patients with anorexia nervosa in the stage of cachexia

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