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Limit Caffeine: Since phentermine already boosts energy, too much coffee or energy drinks may make you feel jittery start with less and adjust as needed

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But it also raises IGF-1, disrupts glucose metabolism, and can accelerate unwanted tissue growth

Safe Alternatives: When You Need Additional Support If tirzepatide alone plateaus after several months of consistent use, evidence supports modest lifestyle intensificationincreased physical activity, structured meal planning, and sleep optimizationbefore adding pharmaceutical layers