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Indeed, it is known that Nrf2 is a master factor for the regulation of antioxidant response elements (ARE) in several antioxidant and phase II detoxifying proteins in different cell types, including nerve cells (Kobayashi and Yamamoto, 2013), and several reports have shown that although DHA itself does not bind Nrf2, it may stimulate transcriptional activity of ARE-containing genes through activation of Nrf2 upon generation of 4-hydroxy-2-hexenal, which indeed activates Nrf2 (Ishikado et al., 2013)

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doi: 10.3390/nu14112275 496 de Jess Romero-PradoMMCuriel-BeltrnJAMiramontes-EspinoMVCardona-MuozEGRios-ArellanoABalam-SalazarLB

Untrained practitioners using low-quality equipment significantly increase the risk of burns, scarring, and pigmentation damage