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Description

139 , 16001607.e2 (2017)

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Researchers performing such work should have relevant expertise in biochemical handling and peptide-focused experiment design

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Studies using cytokine-deficient (knockout) mice

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Intracellular microtubules are known to undergo rapid depolymerization when temperatures fall below physiological levels, reflecting the dependence of microtubule polymerization on GTP hydrolysis and environmental conditions (32, 33)

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His central insight: don't try to deliver the molecule, give the cell what it needs to build the molecule itself

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