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Neuron activity was compromised as the reduction of neural peptide, N-acetylaspartylglutamic acid, amino acid, aminolevulinic acid, and increasing the melanocytes and neurotransmitters metabolites, cysteinyldopa and pyrocatechol (47, 48)

Furthermore, EGCG inhibits CRC cell proliferation and induces apoptosis by blocking the activation of the receptor tyrosine kinases family members EGFR, IGF-1R and VEGFR2 (50)