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Immunofluorescence staining in vitro T3M4 cells and PSC were seeded in gloss bottom dishes and received treatments of different formulations containing 20 M (T3M4 cells) or 10 M (PSC) of TPCA-1 and 50 nM of AsiG for 48 h at pH 6.5, followed by fixation in 4% paraformaldehyde for 10 min at room temperature

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Plant Cell 11: 12771292 Dong Y, Silbermann M, Speiser A, Forieri I, Linster E, Poschet G, Allboje Samami A, Wanatabe M, Sticht C, Teleman AA, et al

Overall, our work demonstrates a key signaling interplay between DA and NE in - and -cells as a novel regulatory pathway for pancreatic hormone release and offers the promise of new therapeutic approaches to treat the dysfunctional secretion of insulin and glucagon by targeting peripheral catecholamine receptors