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Pigmented lesions of the oral cavity: An Update PMC Labial melanotic macule. B). Increased numbers of me lanocytes along Download Scientific Diagram Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown melanotic macule gingiva have had for years COM August 2004 Diagnosis Congenital Melanotic Macule of the Melanocytic Lesions A Guide to Clinical Differential Diagnosis of Oral Mucosal Lesions Continuing Education Course

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