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Erythrocyte GSH increased by 30-35% at the 1,000 mg dose after 6 months (Richie et al., Eur J Nutr, 2015) [12]

Lactone 166 was treated with triphenylphosphine, iodine, and imidazole to give iodolactone 167, whose reduction was followed by an in situ two-carbon Wittig reaction to give unsaturated ester 168

[] The glucose homeostasis is directly regulated by insulin and glucagon

Darinaparsin belongs to the class of organic arsenical compounds that are generally considered less toxic than inorganic ones (Waxman and Anderson, 2001