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A significant gap persists in translating these in-vitro and in-vivo research observations to human subjects on a broader scale

We screened the zf-UBP and DUSP2 domains of USP20 and USP33, as well as the DUSP1-DUSP2 tandem of USP20

For example, decanoic acid (C10), a medium-chain fatty acid, enhances mitochondrial function and biogenesis via PPAR- activation and improves brain energy metabolism

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Fresh frozen cancer tissue (obtained immediately after surgery) from 44 eligible patients, and plasma (taken at preoperative examination or before adjuvant chemotherapy) from 51 cancer patients and the three patients with benign tumors, were used for the study (Fig