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this created a crucial need to understand the mechanism of these types of resistance, this understanding can help developing strategies to overcome tamoxifen resistance

[DOI] [Google Scholar] 188.Wu Min W.M., Sun Yang S.Y., Bi ChongHao B.C., Ji Fang J.F., Li BoRui L.B., Xing JunJie X.J

Silent information regulator 2-related enzyme 1 (SIRT1) is a deacetylase dependent on nicotinamide adenine dinucleotide, which is highly expressed in a variety of tumors and has been proven to inhibit the growth of breast cancer cells (Liu et al., 2009