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A recently published longitudinal study showed that people using metformin had a greater risk of neuropathy [HR = 1.84 (95% CI, 1.62, 2.10)] than those not using metformin [49]

This is highly variable

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Analysis of metabolites information MS data pretreatments were performed using XCMS software after extracting and quantifying metabolites from tumour samples using UPLC-MS/MS 80