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Several studies confirmed the safety of intranasal insulin in patients with mild cognitive impairment and AD [67, 239]

This approach allowed us to identify BolA2 as a PCBP1-interacting protein

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Why Long-Term Safety and Pharmacokinetics Remain Unclear A 2022 rat and dog pharmacokinetic study reported a prototype BPC157 half-life under 30 minutes after IV or IM administration, linear pharmacokinetics in those species, and metabolism into peptide fragments and amino acids [10]