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After 48 h, biofilms were washed once with 1 PBS followed by treatment with different concentrations of 0, 5, 10, 25, and 50 M H 2 O 2 (prepared by diluting an aliquot of 30% (v/v) H 2 O 2 in 1 PBS) for 24 h, at 37C and shaking at 150 rpm

36 showed that the neurotoxic activation of microglia with LPS can be reduced in the presence of elevated UA, an effect shown to be mediated by cellular UA uptake