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Biomaterials delivery strategies to repair degenerated intervertebral discs by regulating the inflammatory microenvironment

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Infusion of Peptide 5, a selective Cx43 hemichannel blocker, 90 min after a 30-min period of bilateral carotid artery occlusion, thus limited brain damage 510

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PEG-it Virus Precipitation Solution (LV810A-1, System Biosciences) was added to the clarified supernatant at a 1:4 ratio (e.g., 3.5 mL PEG-it per 14 mL supernatant), mixed, and incubated overnight at 4 C on a rotator