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Targeting FGFR signaling pathway Although a study suggests that activating endothelial FGFR signaling may offer therapeutic potential by inhibiting TGF--mediated EndMT in hypoxia-PH, 283 a number of studies have demonstrated that inhibiting FGFRs, either through selective inhibitors or broader strategies, can attenuate the hyper-proliferation of PASMCs, prevent further vascular remodeling, and reduce hemodynamic impairments in experimental PAH and idiopathic PH models

Clinical research found various antioxidants, such as EGCG

Since Src kinase activation is mediated by the binding of A 42 to Na,K-ATPase, which also acts as the receptor for cardiotonic steroids, we hypothesized that ouabain may influence the positive feedback loop we found

Pasternak et al., 2008)

(Ill order this too just to try incase it helps him) My deep sleep is good (45-90 minutes), but its not a high percentage of sleep