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Of note, ketones are not substrates for gluconeogenesis, as they are converted into acetyl-CoA upon uptake, which mammals cannot use to synthesize glucose [30]

The release of Hb is due to the accumulation and dissolution of iron-rich erythrocytes in the brain parenchyma, which consequently leads to iron toxicity and induces the production of ROS (Wu et al., 2011), interfering with normal function of cells and resulting in neuronal death (Zecca et al., 2004)

Each vial is independently verified to 99% HPLC purity with a Certificate of Analysis available on request

165 The knockdown of the LD cargo receptor RAB7A can inhibit ferroptosis

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