Abstract Once considered the exclusive property of conjugated molecules, efficient and visible-light luminescence from non-conjugated and nonemissive molecules in the clustered state, known as clusteroluminescence (CL), has attracted much attention recently due to its special photophysical behaviors and behind electronic interactions
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To further establish that R4VPL3-1 induced ferroptotic cell death and test for potential involvement of additional cell death pathways that may mediate R4VPL3-1-induced cell death, we pre-treated A375R melanoma cells either with DMSO (control), or with Z-VAD-FMK (pan-caspase inhibitor), chloroquine (lysosomal inhibitor), or Necrostatin (a necroptosis inhibitor), or Ferr-1 (ferroptosis inhibitor), and subsequently treated the cells with 3M R4VPL3-1
Together, these interventions could support both acute healing and long-term maintenance of digestive health, an important consideration given the central role of gut function in overall wellbeing
Neurol Lett 4(1):16 Group A-REDSR (2004) Impact of antioxidants, zinc, and copper on cognition in the elderly: a randomized, controlled trial