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In summary, the HPA axis is a key component of the MGBA, and a possible mechanism is that VNS modulates PD-related neuropsychiatric symptoms by regulating HPA axis function via the vagus nerve

Immunosenescence, marked by CD28 CD57 + T-cell accumulation, affects treatment outcomes in PWH

2 Tumor microenvironment (TME) and opportunities Cancer consists of a complex environment with heterogenous cells involved in a dissimilar, unpredictable, and mutually interactive patterns of growth